Neuropathy Validation

VALIDATION OF MOUSE MODELS OF DIABETIC NEUROPATHY

The AMDCC Neuropathy Committee has the principal function of developing strategies and protocols for the creation and/or modification of animals models for diabetic complications of the nervous system. This committee develops strategies for creating these animal models using transgenic and knockout technologies. Standard protocols and criteria for the induction, analysis and interpretation of the nervous system pathology are also developed. The commitee is currently evaluating validation criteria of mouse models of Diabetic Neuropathy.